TIPS FOR USING STRENSIQ

You probably have some questions about fitting STRENSIQ® (asfotase alfa) into your routine. If you’re looking for more information, don’t hesitate to talk to your doctor or reach out to OneSource™.

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HOW TO STORE STRENSIQ

Since STRENSIQ is a sensitive enzyme, it is important to store and handle it correctly.

Do
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Store STRENSIQ in its original package in the refrigerator at 36°F to 46°F (2°C to 8°C) until you are ready to use it.
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Protect STRENSIQ from light until you are ready to use it.
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Remove STRENSIQ from the refrigerator 15 to 30 minutes before use, then be sure to use it within 3 hours.

 

Do not
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Do not freeze your STRENSIQ vials. Do not use STRENSIQ if it has been frozen.
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Do not shake your STRENSIQ vials.
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Do not use STRENSIQ after the expiration date printed on the package.
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Remember that STRENSIQ comes in single-use vials, so throw away any extra STRENSIQ left in the vial after your injection.

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TRAVELING WITH STRENSIQ

When traveling with STRENSIQ, keep it refrigerated throughout your trip in its original package at 36°F to 46°F (2° to 8°C). Before you head out on your next getaway, consider the following ideas:

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Plan ahead

Gather your injection supplies and check with your destination to make sure there will be a place to refrigerate STRENSIQ when you get there.

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Keep cool

To maintain its ideal temperature, STRENSIQ may be stored in an insulated cooler with ice or an ice pack. If traveling long distances by plane, call ahead to your airline to find out if refrigeration is provided in-flight or if attendants can provide additional ice.

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Planning a trip? Once prescribed, you will receive an injection starter kit that includes a travel letter that can be shown to airline staff to make sure your STRENSIQ is handled with care. You can also download a travel letter here.

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Man sitting in home while smiling and talking to camera

QUESTIONS?

Watch our Traveling With STRENSIQ FAQ video.

Enroll in OneSource to get personalized patient support from Alexion:

READY TO GET STARTED?

Once your doctor prescribes STRENSIQ, Alexion will be there to guide you every step of the way. See the resources available as you make STRENSIQ part of your routine.

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IMPORTANT SAFETY INFORMATION & INDICATION

STRENSIQ may cause serious side effects, including

  • Serious allergic (hypersensitivity) reactions happened in some people who use STRENSIQ. Stop using STRENSIQ and go to the nearest hospital emergency room right away if you or your loved one have any of the signs and symptoms of a serious allergic reaction, including
    • Difficulty breathing
    • Swelling of your eyes, lips, or tongue
    • Hives
    • Feeling faint
    • Nausea or vomiting
    • Dizziness
    • Itching of your lips, tongue, or throat
    • Choking sensation
  • Skin thickening or pits at the injection site (lipodystrophy) has happened several months after using STRENSIQ.
  • Calcium buildup in the eyes and kidneys can occur if you or your loved one have HPP. Your healthcare provider should check the eyes and kidneys while you or your loved one use STRENSIQ.
  • Decreased efficacy. Contact your healthcare provider if you or your loved one notice STRENSIQ is no longer working or experience worsening symptoms of HPP (e.g., increased respiratory support, increased difficulty walking, new fractures).

The most common side effects of STRENSIQ include local skin injection-site reactions (red skin patches, bruising, color change, pain, itching, thinning, swelling, pits, and bumps) and calcium buildup in your eyes and kidneys.

Strensiq may affect other lab test results, therefore it is important that you present your Medical Alert Card to your healthcare team so they are aware that you are being treated with an alkaline phosphatase (ALP) replacement therapy which may cause incorrect results on certain laboratory tests.

Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding or plan to breastfeed.

These are not all the possible side effects of STRENSIQ. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to the US Food and Drug Administration at 1‑800‑FDA‑1088.

INDICATION
What is STRENSIQ?
Strensiq is a prescription medicine used to treat people with perinatal/infantile- and juvenile-onset hypophosphatasia (HPP).

Please see STRENSIQ full Prescribing Information, including Patient Information and Instructions for Use.
IMPORTANT SAFETY INFORMATION & INDICATION

STRENSIQ may cause serious side effects, including

  • Serious allergic (hypersensitivity) reactions happened in some people who use STRENSIQ. Stop using STRENSIQ and go to the nearest hospital emergency room right away if you or your loved one have any of the signs and symptoms of a serious allergic reaction, including
    • Difficulty breathing
    • Swelling of your eyes, lips, or tongue
    • Hives
    • Feeling faint
    • Nausea or vomiting
    • Dizziness
    • Itching of your lips, tongue, or throat
    • Choking sensation
  • Skin thickening or pits at the injection site (lipodystrophy) has happened several months after using STRENSIQ.
  • Calcium buildup in the eyes and kidneys can occur if you or your loved one have HPP. Your healthcare provider should check the eyes and kidneys while you or your loved one use STRENSIQ.
  • Decreased efficacy. Contact your healthcare provider if you or your loved one notice STRENSIQ is no longer working or experience worsening symptoms of HPP (e.g., increased respiratory support, increased difficulty walking, new fractures).

The most common side effects of STRENSIQ include local skin injection-site reactions (red skin patches, bruising, color change, pain, itching, thinning, swelling, pits, and bumps) and calcium buildup in your eyes and kidneys.

Strensiq may affect other lab test results, therefore it is important that you present your Medical Alert Card to your healthcare team so they are aware that you are being treated with an alkaline phosphatase (ALP) replacement therapy which may cause incorrect results on certain laboratory tests.

Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding or plan to breastfeed.

These are not all the possible side effects of STRENSIQ. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to the US Food and Drug Administration at 1‑800‑FDA‑1088.

INDICATION
What is STRENSIQ?
Strensiq is a prescription medicine used to treat people with perinatal/infantile- and juvenile-onset hypophosphatasia (HPP).

Please see STRENSIQ full Prescribing Information, including Patient Information and Instructions for Use.