TREAT WITH CONFIDENCE

STRENSIQ® (asfotase alfa) is an injection given under the skin (called a subcutaneous injection) and can be conveniently taken at home or wherever you go.

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HOW STRENSIQ IS DOSED

STRENSIQ is dosed in milligrams based on weight. You and your doctor will decide which dosage is right for you. As your weight changes, your dosage may also change depending on your doctor’s recommendations.

STRENSIQ is dosed as either:

Dosing options
Dosing options

It is important to use STRENSIQ as described in the Patient Prescribing Information and Instructions for Use, or as instructed by your doctor, nurse, and/or pharmacist.

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TIPS FOR SMOOTH INJECTION

Whether you are injecting STRENSIQ into yourself or someone you care for, it’s normal to feel anxious.

An important part of the process is for you to feel confident injecting STRENSIQ. If you need anything clarified about injection, don’t be afraid to ask questions or have your doctor review something more than once.

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STRENSIQ can be injected under the skin of the stomach area, upper arms, upper legs, or buttocks.


STRENSIQ should not be injected into the buttocks for infants.

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Choose a different area each time you inject to help avoid irritation at the injection site.

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Do not inject STRENSIQ into skin that is red, hot, or swollen.

Injection sites

STRENSIQ may cause serious side effects, including serious allergic (hypersensitivity) reactions and skin thickening or pits at the injection site (lipodystrophy).

INJECTION RESOURCES

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Injection IQ

Read a complete guide on injecting STRENSIQ into yourself or someone you care for.

DOWNLOAD GUIDE
Injection starter kit
In your first shipment of STRENSIQ, you will receive an injection starter kit. This kit provides an injection supplies mat, injection site tracker, calendar, and other tools that will help establish a routine with STRENSIQ.
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OneSource™ Case Managers are always available to talk through questions or concerns about injections. Reach out at 1.888.765.4747, OneSource@alexion.com, or AlexionOneSource.com.

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Boy sitting at desk while smiling and talking to camera

FINDING INJECTION COURAGE

Hear how people learned to inject STRENSIQ with confidence.

PREPARING FOR SELF-INJECTION

Some people with hypophosphatasia (HPP) may feel like the condition takes away their independence. Symptoms of HPP can limit their ability to do things they enjoy, feel included in activities, or simply live a more comfortable lifestyle.

Self-injecting STRENSIQ can take back some of this lost independence. Controlling injections can be empowering for some people, but it can also seem like a scary step to take. Some helpful tips to prepare for self-injections include:

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Ask questions
If your doctor decides you or someone you care for is ready to self-inject STRENSIQ, do not hesitate to ask questions. It is important to ensure everyone involved is comfortable making this transition.
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Set a routine
Establishing a routine can help someone adapt to remembering their injections. For example, some may prefer to inject in the morning before eating breakfast, while others may wish to inject at night before going to bed.
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Monitor at first
It may also be beneficial for a caregiver to monitor the first few self-injections. Having someone who is familiar with the injection process may relieve some anxiety about self-injecting.

LOOKING FOR MORE TIPS?

Feeling uneasy about fitting STRENSIQ into your routine is normal. Check out more guidelines to help you feel confident as you begin and continue treatment.

TIPS FOR USING STRENSIQ
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IMPORTANT SAFETY INFORMATION & INDICATION

STRENSIQ may cause serious side effects, including

  • Serious allergic (hypersensitivity) reactions happened in some people who use STRENSIQ. Stop using STRENSIQ and go to the nearest hospital emergency room right away if you or your loved one have any of the signs and symptoms of a serious allergic reaction, including
    • Difficulty breathing
    • Swelling of your eyes, lips, or tongue
    • Hives
    • Feeling faint
    • Nausea or vomiting
    • Dizziness
    • Itching of your lips, tongue, or throat
    • Choking sensation
  • Skin thickening or pits at the injection site (lipodystrophy) has happened several months after using STRENSIQ.
  • Calcium buildup in the eyes and kidneys can occur if you or your loved one have HPP. Your healthcare provider should check the eyes and kidneys while you or your loved one use STRENSIQ.
  • Decreased efficacy. Contact your healthcare provider if you or your loved one notice STRENSIQ is no longer working or experience worsening symptoms of HPP (e.g., increased respiratory support, increased difficulty walking, new fractures).

The most common side effects of STRENSIQ include local skin injection-site reactions (red skin patches, bruising, color change, pain, itching, thinning, swelling, pits, and bumps) and calcium buildup in your eyes and kidneys.

Strensiq may affect other lab test results, therefore it is important that you present your Medical Alert Card to your healthcare team so they are aware that you are being treated with an alkaline phosphatase (ALP) replacement therapy which may cause incorrect results on certain laboratory tests.

Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding or plan to breastfeed.

These are not all the possible side effects of STRENSIQ. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to the US Food and Drug Administration at 1‑800‑FDA‑1088.

INDICATION
What is STRENSIQ?
Strensiq is a prescription medicine used to treat people with perinatal/infantile- and juvenile-onset hypophosphatasia (HPP).

Please see STRENSIQ full Prescribing Information, including Patient Information and Instructions for Use.
IMPORTANT SAFETY INFORMATION & INDICATION

STRENSIQ may cause serious side effects, including

  • Serious allergic (hypersensitivity) reactions happened in some people who use STRENSIQ. Stop using STRENSIQ and go to the nearest hospital emergency room right away if you or your loved one have any of the signs and symptoms of a serious allergic reaction, including
    • Difficulty breathing
    • Swelling of your eyes, lips, or tongue
    • Hives
    • Feeling faint
    • Nausea or vomiting
    • Dizziness
    • Itching of your lips, tongue, or throat
    • Choking sensation
  • Skin thickening or pits at the injection site (lipodystrophy) has happened several months after using STRENSIQ.
  • Calcium buildup in the eyes and kidneys can occur if you or your loved one have HPP. Your healthcare provider should check the eyes and kidneys while you or your loved one use STRENSIQ.
  • Decreased efficacy. Contact your healthcare provider if you or your loved one notice STRENSIQ is no longer working or experience worsening symptoms of HPP (e.g., increased respiratory support, increased difficulty walking, new fractures).

The most common side effects of STRENSIQ include local skin injection-site reactions (red skin patches, bruising, color change, pain, itching, thinning, swelling, pits, and bumps) and calcium buildup in your eyes and kidneys.

Strensiq may affect other lab test results, therefore it is important that you present your Medical Alert Card to your healthcare team so they are aware that you are being treated with an alkaline phosphatase (ALP) replacement therapy which may cause incorrect results on certain laboratory tests.

Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding or plan to breastfeed.

These are not all the possible side effects of STRENSIQ. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to the US Food and Drug Administration at 1‑800‑FDA‑1088.

INDICATION
What is STRENSIQ?
Strensiq is a prescription medicine used to treat people with perinatal/infantile- and juvenile-onset hypophosphatasia (HPP).

Please see STRENSIQ full Prescribing Information, including Patient Information and Instructions for Use.